George P Chrousos Selected Research

Mineralocorticoids

6/2014	Adrenal insufficiency.
5/2008	Generalized glucocorticoid resistance: clinical aspects, molecular mechanisms, and implications of a rare genetic disorder.
10/2007	A novel point mutation in helix 11 of the ligand-binding domain of the human glucocorticoid receptor gene causing generalized glucocorticoid resistance.
6/2005	A novel point mutation in the ligand-binding domain (LBD) of the human glucocorticoid receptor (hGR) causing generalized glucocorticoid resistance: the importance of the C terminus of hGR LBD in conferring transactivational activity.
6/2004	Familial/sporadic glucocorticoid resistance: clinical phenotype and molecular mechanisms.
4/2004	Natural glucocorticoid receptor mutants causing generalized glucocorticoid resistance: molecular genotype, genetic transmission, and clinical phenotype.
1/2004	Glucocorticoid and mineralocorticoid receptors and associated diseases.
7/2002	Adrenomedullary function may predict phenotype and genotype in classic 21-hydroxylase deficiency.
4/2002	Female pseudohermaphroditism caused by a novel homozygous missense mutation of the GR gene.

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George P Chrousos Research Topics

Disease

46	Inflammation (Inflammations) 06/2022 - 04/2002
43	Obesity 10/2022 - 01/2003
36	Insulin Resistance 02/2022 - 05/2002
23	Type 2 Diabetes Mellitus (MODY) 10/2022 - 06/2005
20	Glucocorticoid Receptor Deficiency 01/2022 - 04/2002
19	Neoplasms (Cancer) 05/2022 - 01/2002
19	Metabolic Syndrome (Dysmetabolic Syndrome X) 03/2018 - 05/2002
16	Overweight 06/2022 - 11/2005
16	Hypertension (High Blood Pressure) 01/2022 - 09/2002
11	Hypersensitivity (Allergy) 12/2015 - 12/2002
10	Fatigue 01/2022 - 03/2002
10	Congenital Adrenal Hyperplasia (Hyperplasia, Congenital Adrenal) 01/2017 - 02/2002
10	Cushing Syndrome 05/2014 - 04/2002
10	Hyperandrogenism 01/2011 - 02/2002
8	Pediatric Obesity 08/2021 - 07/2008
8	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 01/2021 - 09/2007
8	Cardiovascular Diseases (Cardiovascular Disease) 12/2019 - 08/2004
8	Atherosclerosis 07/2014 - 10/2004
7	COVID-19 01/2022 - 10/2020
7	Sleep Initiation and Maintenance Disorders (Insomnia) 01/2022 - 03/2002
7	Hyperaldosteronism (Conn Syndrome) 06/2020 - 11/2011
7	Vitamin D Deficiency 01/2018 - 07/2012
6	Body Weight (Weight, Body) 10/2022 - 11/2005
6	Pain (Aches) 05/2022 - 10/2002
6	Adrenal Insufficiency (Adrenal Gland Hypofunction) 01/2022 - 02/2002
6	Infections 07/2021 - 12/2002
6	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 11/2020 - 02/2013
6	Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal) 01/2019 - 05/2002
6	Osteoporosis 06/2018 - 10/2002
6	Abdominal Obesity 01/2015 - 06/2003
6	Sleepiness 01/2014 - 03/2002
5	Disease Progression 04/2022 - 09/2002
5	Chronic Disease (Chronic Diseases) 01/2022 - 12/2010
5	Breast Neoplasms (Breast Cancer) 02/2020 - 10/2005
5	Sleep Wake Disorders 01/2020 - 03/2002
5	Necrosis 07/2018 - 11/2012
5	Congenital adrenal hyperplasia due to 21 hydroxylase deficiency 01/2017 - 02/2002
5	Acquired Immunodeficiency Syndrome (AIDS) 09/2014 - 12/2002
5	Lipodystrophy 09/2014 - 06/2003
5	Disorders of Excessive Somnolence (Hypersomnia) 10/2013 - 03/2002
5	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 06/2008 - 04/2002
4	Mental Disorders (Mental Disorder) 05/2022 - 02/2002
4	Hypoglycemia (Reactive Hypoglycemia) 01/2019 - 02/2004
4	Birth Weight (Birth Weights) 04/2017 - 03/2004
4	Essential Hypertension 08/2015 - 06/2007
4	Sleep Apnea Syndromes (Sleep Apnea) 01/2012 - 03/2002
3	Nervous System Diseases (Neurological Disorders) 11/2021 - 12/2002
3	Autism Spectrum Disorder 06/2021 - 08/2007
3	Autistic Disorder (Autism) 06/2021 - 08/2007
3	Anxiety Disorders (Anxiety Disorder) 05/2021 - 01/2010
3	Parkinson Disease (Parkinson's Disease) 01/2021 - 08/2019
3	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2021 - 07/2007
3	Alzheimer Disease (Alzheimer's Disease) 01/2021 - 01/2020

Drug/Important Bio-Agent (IBA)

55	Hydrocortisone (Cortisol)FDA LinkGeneric 05/2022 - 02/2002
51	GlucocorticoidsIBA 01/2022 - 03/2002
25	Hormones (Hormone)IBA 01/2022 - 08/2003
25	Insulin (Novolin)FDA Link 01/2021 - 05/2002
24	Biomarkers (Surrogate Marker)IBA 02/2022 - 02/2002
22	CytokinesIBA 01/2022 - 03/2002
20	Proteins (Proteins, Gene)FDA Link 04/2022 - 09/2002
20	Adrenocorticotropic Hormone (ACTH)FDA Link 01/2022 - 02/2002
19	Interleukin-6 (Interleukin 6)IBA 01/2022 - 03/2002
14	Vitamin D FDA LinkGeneric 06/2022 - 03/2012
14	C-Reactive ProteinIBA 02/2022 - 01/2005
14	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 02/2004
14	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 04/2016 - 06/2003
13	AldosteroneIBA 01/2022 - 05/2002
13	LeptinIBA 01/2021 - 05/2002
12	Corticotropin-Releasing HormoneIBA 01/2022 - 02/2002
12	LipidsIBA 01/2020 - 11/2005
12	AdipokinesIBA 03/2017 - 07/2008
11	Biological ProductsIBA 06/2022 - 03/2007
11	AdiponectinIBA 03/2017 - 10/2005
9	SteroidsIBA 02/2019 - 09/2002
9	MineralocorticoidsIBA 06/2014 - 04/2002
8	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2021 - 07/2005
8	AndrogensIBA 11/2020 - 04/2002
8	CatecholaminesIBA 04/2013 - 10/2002
6	Dexamethasone (Maxidex)FDA LinkGeneric 01/2022 - 04/2002
6	glucocorticoid receptor alphaIBA 01/2020 - 04/2002
6	HDL CholesterolIBA 12/2019 - 08/2010
6	Triglycerides (Triacylglycerol)IBA 12/2019 - 05/2012
6	InterleukinsIBA 01/2017 - 01/2005
6	Messenger RNA (mRNA)IBA 08/2015 - 05/2009
5	Pharmaceutical PreparationsIBA 01/2022 - 01/2006
5	SaltsIBA 06/2020 - 02/2002
5	hydroxide ionIBA 10/2018 - 01/2003
5	Lipocalin-2IBA 01/2017 - 07/2008
5	LigandsIBA 05/2014 - 06/2002
5	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 08/2006 - 03/2002
4	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 09/2002
4	Growth Hormone (Somatotropin)IBA 03/2019 - 02/2003
4	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 11/2014 - 04/2002
4	CorticosteroneIBA 06/2013 - 06/2002
4	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2010 - 08/2004
3	AngiotensinsIBA 09/2021 - 06/2011
3	ReninIBA 08/2021 - 08/2015

Therapy/Procedure

26	Therapeutics 04/2022 - 09/2002
4	Glycemic Control 12/2020 - 02/2013
4	Blood Component Removal (Apheresis) 01/2020 - 01/2019